研究成果(2019)

論文業績(2019年)

Takada K, Kashiwagi S, Asano Y, Goto W, Takahashi K, Fujita H, Takashima T, Tomita S, Hirakawa K, Ohira M : Clinical verification of the relationship between smoking and the immune microenvironment of breast cancer. J Transl Med 17(1):13 (2019)

Yamaguchi T, Watanabe A, Tanaka M, Shiota M, Osada-Oka M, Sano S, Yoshiyama M, Miura K, Kitajima S, Matsunaga S, Tomita S, Iwao H, Izumi Y : A dipeptidyl peptidase-4 (DPP-4) inhibitor, linagliptin, attenuates cardiac dysfunction after myocardial infarction independently of DPP-4.
J Pharmacol Sci 139(2):112-119 (2019)

Takada K, Kashiwagi S, Asano Y, Goto W, Takahashi K, Shibutani M, Amano R, Takashima T, Tomita S, Hirakawa K, Ohira M : Prognostic Value of Quality of Life in Endocrine Therapy for Elderly Patients With Breast Cancer: A Retrospective Study.
Anticancer Res 39(6):2941-2950 (2019)

Takada K, Kashiwagi S, Asano Y, Goto W, Takahashi K, Fujita H, Takashima T, Tomita S, Hirakawa K, Ohira M : Verification of the effects of calcium channel blockers on the immune microenvironment of breast cancer. BMC Cancer 19(1):615 (2019)

Nakatani K, Nakagami-Yamaguchi E, Shinoda Y, Tomita S, Nakatani T: Improving the safety of high-concentration potassium chloride injection. BMJ Open Qual 8(2):e000666 (2019)

Kashiwagi S, Asano Y, Takahashi K, Shibutani M, Amano R, Tomita S, Hirakawa K, Ohira M : Clinical Outcomes of Recombinant Human-soluble Thrombomodulin Treatment for Disseminated Intravascular Coagulation in Solid Tumors. Anticancer Res 39(5):2259-2264 (2019)

Goto W, Kashiwagi S, Asano Y, Takada K, Takahashi K, Fujita H, Takashima T, Shibutani M, Amano R, Tomita S, Hirakawa K, Ohira M : The Effects of Eribulin on Breast Cancer Microenvironment Identified Using Eribulin-resistant Breast Cancer Cell Lines.
Anticancer Res 39(8):4031-4041 (2019)

Nishide S, Matsunaga S, Shiota M, Yamaguchi T, Kitajima S, Maekawa Y, Takeda N, Tomura M, Uchida J, Miura K, Nakatani T, Tomita S : Controlling the Phenotype of Tumor-Infiltrating Macrophages via the PHD-HIF Axis Inhibits Tumor Growth in a Mouse Model.
iScience 19:940-954 (2019)

Takada K, Kashiwagi S, Asano Y, Goto W, Takahashi K, Shibutani M, Amano R, Takashima T, Tomita S, Hirakawa K, Ohira M : Clinical Evaluation of Dynamic Monitoring of Neutrophil-to-lymphocyte and Platelet-to-lymphocyte Ratios in Primary Endocrine Therapy for Advanced Breast Cancer. Anticancer Res 39(10):5581-5588 (2019)

Ishikawa H, Izumiya Y, Shibata A, Ichikawa Y, Yamaguchi T, Yamaguchi Y, Kitada R, Iwata S, Ehara S, Tomita S, Hanatani A, Yoshiyama M : Soluble urokinase-type plasminogen activator receptor represents exercise tolerance and predicts adverse cardiac events in patients with heart failure. Heart Vessels Vessels 18: (2019). doi: 10.1007/s00380-019-01538-3.

Nakagawa T, Furukawa Y, Hayashi T, Nomura A, Yokoe S, Moriwaki K, Kato R, Ijiri Y, Yamaguchi T, Izumi Y, Yoshiyama M, Asahi M : Augmented O-GlcNAcylation attenuates intermittent hypoxia-induced cardiac remodeling through the suppression of NFAT and NF-κB activities in mice.
Hypertens Res42(12):1858-1871(2019)

Osada-Oka M, Goda N, Saiga H, Yamamoto M, Takeda K, Ozeki Y, Yamaguchi T, Soga T, Tateishi Y, Miura K, Okuzaki D, Kobayashi K, Matsumoto S : Metabolic adaptation to glycolysis is a basic defense mechanism of macrophages for Mycobacterium tuberculosis infection.
Int Immunol.8;31(12):781-793(2019)

学会・研究会発表(2019年)

第48回日本心脈管作動物質学会、2月7-8日、富山
リナグリプチンはdipeptidyl peptidase-4非依存的に心筋梗塞後のリモデリングを抑制する
山口 雄大

第92回日本薬理学会年会、3月14-16日、大阪
PHD阻害薬によるがん微小環境と腫瘍免疫への影響
腫瘍環境改変によるマクロファージ活性化機構の解明
松永慎司
Percutaneous Treatment of Carbon Dioxide Gas Mist Suppresses the Development of Right Ventricular Dysfunction in Monocrotaline-Induced Pulmonary Hypertensive Rats
山口 雄大

第92回日本細菌学会総会、4月23-25日、北海道
Exploring the Role of Mycobacterial Membrane Vesicles toward Vaccine Development
山口 雄大

第17回がんとハイポキシア研究会、11月16-17日、大阪
担癌モデルマウスに対するPHD阻害剤の効果検討
松永慎司