2024
- (44) Copper Complexes with Protein-Based N-Donor Ligands as cis-Selective Nascent Cyclopropanases
Nobutaka Fujieda*, Atsuki Matsuo, Shinobu Itoh*
Chem. Eur. J., xxx, xxxx (2024). in press. 10.1002/chem.202402803.[Link]
- (43) A thiopyridine-bound mirror-image copper center in an artificial non-heme metalloenzyme
Yoshitsugu Morita*, Hiroki Kubo, Ryusei Matsumoto, Nobutaka Fujieda*
J. Inorg. Biochem., 260, 112694 (2024). 10.1016/j.jinorgbio.2024.112694. [Link]
- (42) Asymmetric Michael addition catalysed by copper–amyloid complexes
Nobutaka Fujieda*, Atsushi Tonomura, Tomofumi Mochizukic, Shinobu Itoh*
RSC Adv., 14 (1), 206–210 (2024). 10.1039/D3RA07900G [Link]
2023
- (41) An Artificial Metallolyase with Pliable 2-His-1-Carboxylate Facial Triad for Stereoselective Michael Addition
Ryusei Matsumoto, Saho Yoshioka, Miho Yuasa, Yoshitsugu Morita, Genji Kurisu, Nobutaka Fujieda*
Chem. Sci., 14 (14), 3932–3937 (2023). 10.1039/D2SC06809E [Link]
2020
- (40) Copper–Oxygen Dynamics in the Tyrosinase Mechanism
Nobutaka Fujieda*, Kyohei Umakoshi, Yuta Ochi, Yosuke Nishikawa, Sachiko Yanagisawa, Minoru Kubo, Genji Kurisu, Shinobu Itoh*
Angew. Chem. Int., 59 (32), 13385–13390 (2020). 10.1002/anie.202004733 [Link]
- (39) Cupin Variants as a Macromolecular Ligand Library for Stereoselective Michael Addition of Nitroalkanes
Nobutaka Fujieda*, Haruna Ichihashi, Miho Yuasa, Yosuke Nishikawa, Genji Kurisu, Shinobu Itoh*
Angew. Chem. Int., 59 (20), 7717–7720 (2020). 10.1002/anie.202000129 [Link]
2017
- (38) A Well-Defined Osmium-Cupin Complex: Hyperstable Artificial Osmium Peroxygenase
Nobutaka Fujieda*, Takumi Nakano, Yuki Taniguchi, Haruna Ichihashi, Hideki Sugimoto, Yuma Morimoto, Yosuke Nishikawa, Genji Kurisu, and Shinobu Itoh*
J. Am. Chem. Soc., 139 (14), 5149–5155 (2017). 10.1021/jacs.7b00675
2016
- (37) Controlling Dicopper Protein Functions
Nobutaka Fujieda and Shinobu Itoh*
Bull. Chem. Soc. Jpn., 89 (7), 733–742 (2016). 10.1246/bcsj.20150444
2015
- (36) Fungal Tyrosinase
Nobutaka Fujieda and Shinobu Itoh*
In Encyclopedia of Inorganic and Bioinorganic Chemistry, R. Huber; Poulos, T.; K.Wieghardt, Eds.; John Wiley & Sons, Ltd: Chichester, UK, 1–8 (2015). 10.1246/bcsj.20150444 - (35) Enzyme Repurposing of a Hydrolase as an Emergent Peroxidase upon Metal Binding
Nobutaka Fujieda*, Jonas Schätti, Edward Stuttfeld, Kei Ohkubo, Timm Maier, and Thomas R. Ward*
Chem. Sci., 6 (34), 4060–4065 (2015). 10.1039/C5SC01065A - (34) Generation, Characterization, and Reactivity of a CuII−Alkylperoxide/Anilino Radical Complex: Insight into the O−O Bond Cleavage Mechanism
Sayantan Paria, Takehiro Ohta, Yuma Morimoto, Takashi Ogura, Hideki Sugimoto, Nobutaka Fujieda, Kei Goto, Kaori Asano, Takeyuki Suzuki, and Shinobu Itoh*
J. Am. Chem. Soc., 137 (34), 10870–10873 (2015). 10.1021/jacs.5b04104 - (33) Direct Hydroxylation of Benzene to Phenol Using Hydrogen Peroxide Catalyzed by Nickel Complexes Supported by Pyridylalkylamine Ligands
Yuma Morimoto, Shuji Bunno, Nobutaka Fujieda, Hideki Sugimoto, and Shinobu Itoh*
J. Am. Chem. Soc., 137 (18), 5867-5870 (2015). 10.1021/jacs.5b01814 - (32) Redox behavior of novel nickel and palladium complexes supported by trianionic non-innocent ligand containing β-diketiminate and phenol groups
Yuma Morimoto, June Takaichi, Shinichi Hanada, Kei Ohkubo, Hideki Sugimoto, Nobutaka Fujieda, Shunichi Fukuzumi and Shinobu Itoh*
J. Porphyrins Phthalocyanines, 19, 377–387 (2015). 10.1142/S1088424615500248
2014
- (31) Geometric Control of Nuclearity in Copper(I)/Dioxygen Chemistry
Tsukasa Abe, Yuma Morimoto, Tetsuro Tano, Kaoru Mieda, Hideki Sugimoto, Nobutaka Fujieda, Takashi Ogura, and Shinobu Itoh*
Inorg. Chem., 53 (16), 8786-8794 (2014). 10.1021/ic501461n - (30) Redox Chemistry of Nickel(II)-Complexes Supported by a Series of Non-innocent β-Diketiminate Ligands
June Takaichi, Yuma Morimoto, Kei Ohkubo, Chizu Shimokawa, Takayuki Hojo, Seiji Mori, * Haruyasu Asahara, Hideki Sugimoto, Nobutaka Fujieda, Nagatoshi Nishiwaki, Shunichi Fukuzumi, and Shinobu Itoh*
Inorg. Chem., 53 (12), 6159-6169 (2014). 10.1021/ic5006693
2013
- (29) Redox Properties of Mononuclear Copper(II)-Superoxide Complex
Tetsuro Tano, Yuri Okubo, Atsushi Kunishita, Minoru Kubo, Hideki Sugimoto, Nobutaka Fujieda, Takashi Ogura, and Shinobu Itoh*
Inorg. Chem., 52 (18), 10431-10437 (2013). 10.1021/ic401261z - (28) Crystal Structures Of Copper-Depleted And Copper-Bound Fungal Pro-Tyrosinase: Insights Into Endogenous Cysteine-Dependent Copper Incorporation
Nobutaka Fujieda, Shintaro Yabuta, Takuya Ikeda, Takuji Oyama, Norifumi Muraki, Genji Kurisu,* and Shinobu Itoh*
J. Biol. Chem., 288 (30), 22128-22140 (2013). 10.1074/jbc.M113.477612 - (27) Copper Complexes of the Non-innocent β-Diketiminate Ligand Containing Phenol Groups
June Takaichi, Kei Ohkubo, Hideki Sugimoto, Motohiro Nakano, Daisuke Usa, Hiroaki Maekawa, Nobutaka Fujieda, Nagatoshi Nishiwaki, Shu Seki, Shunichi Fukuzumi, and Shinobu Itoh＊
Dalton Trans., 41 (7), 2438-2444 (2013). 10.1039/C2DT32413J - (26) Activation Mechanism of MelB Tyrosinase from Aspergillus oryzae by Acidic Treatment
Nobutaka Fujieda,* Michiaki Murata, Shintaro Yabuta, Takuya Ikeda, Chizu Shimokawa, Yukihiro Nakamura, Yoji Hata, Shinobu Itoh*
J. Biol. Inorg. Chem., 18 (1), 19-26 (2013). 10.1007/s00775-012-0945-5
2012
- (25) Active Site Models for the CuB Site of Peptidylclycine -Hydroxylating Monooxygenase and Dopamine -Monooxygenase
Atsushi Kunishita, Mehmed Z. Ertem, Yuri Okubo, Tetsuro Tano, Hideki Sugimoto, Kei Ohkubo, Nobutaka Fujieda, Shuichi Fukuzumi, Christopher J. Cramer,* and Shinobu Itoh*
Inorg. Chem., 51 (17), 9465-9480 (2012). 10.1021/ic301272h - (24) Heterolytic Alkylhydroperoxide O–O Bond Cleavage by Copper(I) Complexes
Tetsuro Tano, Hideki Sugimoto, Nobutaka Fujieda, and Shinobu Itoh*
Eur. J. Inorg. Chem., 2012 (26), 4099–4103 (2012). 10.1002/ejic.201200555 - (23) Copper(I)-Dioxygen Reactivity in a Sterically Demanding Tripodal Tetradentate tren Ligand. Formation and Reactivity of a Mononuclear Copper(II) End-on Superoxo Complex
Yuki Kobayashi, Kei Okubo, Takashi Nomura, Minoru Kubo, Nobutaka Fujieda, Hideki Sugimoto, Shunichi Fukuzumi, Kei Goto, Takashi Ogura, and Shinobu Itoh*
Eur. J. Inorg. Chem., 2012 (29), 4574-4578 (2012). [Cover Picture] 10.1002/ejic.201200177 - (22) Artificial Dicopper Oxidase: Rational Reprogramming of Bacterial Metallo-β-lactamase into a Catechol Oxidase
Nobutaka Fujieda,* Atsushi Hasegawa, Kenichi Ishihama, and Shinobu Itoh*
Chem. Asian J., 7 (6), 1203–1207 (2012). [Special Issue of 150 years of German–Japanese friendship] 10.1002/asia.201101014 - (21) Multifunctions of MelB, a Fungal Tyrosinase from Aspergillus oryzae
Nobutaka Fujieda,* Michiaki Murata, Shintaro Yabuta, Takuya Ikeda, Chizu Shimokawa, Yukihiro Nakamura, Yoji Hata, and Shinobu Itoh*
ChemBioChem, 13 (2), 193–201 (2012).
2011
- (20) Reactivity of Copper(II)-alkylperoxo Complexes.
Tetsuro Tano, Mehmed Z. Ertem, Satoru Yamaguchi, Atsushi Kunishita, Hideki Sugimoto, Nobutaka Fujieda, Takashi Ogura, Christopher J. Cramer,* and Shinobu Itoh*
Dalton Trans., 40 (40), 10326–10336 (2011). Front Cover Picture, Hot Article - (19) Post-translational His-Cys Cross Linkage Formation in Tyrosinase Induced by Copper(II)-Peroxo Species.
Nobutaka Fujieda, Takuya Ikeda, Michiaki Murata, Sachiko Yanagisawa, Shigetoshi Aono, Kei Ohkubo, Satoshi Nagao, Takashi Ogura, Shun Hirota, Shunichi Fukuzumi, Yukihiro Nakamura, Yoji Hata, and Shinobu Itoh*
J. Am. Chem. Soc., 133 (5), 1180–1183 (2011). - (18) Reactions of Copper(II)-Phenol Systems with O2. Models for TPQ Biosynthesis in Copper Amine Oxidases.
Kae Tabuchi, Mehmed Z. Ertem, Hideki Sugimoto, Atsushi Kunishita, Tetsuro Tano, Nobutaka Fujieda, Christopher J. Cramer*, and Shinobu Itoh*
Inorg. Chem., 50 (5), 1633–1647 (2011).
2010
- (17) Five Monomeric Hemocyanin Subunits from Portunus trituberculatus: Purification, Spectroscopic Characterization, and Quantitative Evaluation of Phenol Monooxygenase Activity.
Nobutaka Fujieda, Aki Yakiyama, and Shinobu Itoh*
Biochem. Biophys. Acta, 1804, 2128-2135 (2010). - (16) Oxygenation Chemistry at Mononuclear Copper(II)-Hydroquinone Sysetm with O2.
Kae Tabuchi, Hideki Sugimoto, Atsushi Kunishita, Nobutaka Fujieda, and Shinobu Itoh*
Inorg. Chem. 49 (15), 6820–6822 (2010). - (15) Catalytic Oxygenation of Phenols by Arthropod Hemocyanin, an Oxygen Carrier Protein, from Portunus trituberculatus.
Nobutaka Fujieda, Aki Yakiyama, and Shinobu Itoh*
Dalton Trans. 39 (12), 3083–3092 (2010). - (14) Site-directed mutation at residues near the catalytic site of histamine dehydrogenase from Nocardioides simplex and its effects on substrate inhibition.
Maiko Tsutsumi, Noriaki Tsuse, Nobutaka Fujieda, and Kenji Kano*
J. Biochem., 147(2), 257-264 (2010).
2009
- (13) A single circularly permuted GFP sensor for inositol-1,3,4,5-tetrakisphosphate based on a split PH domain.
Reiko Sakaguchi, Takashi Endoh, Seigo Yamamoto, Kazuki Tainaka, Kenji Sugimoto, Nobutaka Fujieda, Shigeki Kiyonaka, Yasuo Mori, and Takashi Morii*
Bioorg. Med. Chem., 17, 7381-7386 (2009).
2008
- (12) The Silent Form of Quinohemoprotein Amine Dehydrogenase from Paracoccus denitrificans.
Nobutaka Fujieda*, Megumi Mori, Tokuji Ikeda, and Kenji Kano
Biosci. Biotech. Biochem., 73(3), 524-529 (2008). - (11) Bioelectrochemical Determination at Histamine Dehydrogenase-based Electrodes.
Yamada, R., Nobutaka Fujieda, Maiko Tsutsumi, Seiya Tsujimura, Osamu Shirai and Kenji Kano*
Electrochemistry, 76(8), 600-602 (2008). - (10) Context-dependent Fluorescence Detection of a Phosphorylated Tyrosine Residue by a Ribonucleopeptide
Tetsuya Hasegawa, Masaki Hagihara, Masatora Fukuda, Shun Nakano, Nobutaka Fujieda and Takashi Morii*
J. Am. Chem. Soc, 130(27), 8804-8812 (2008). - (9) Thermodynamic Redox Properties Governing the Half-reduction Characteristics of Histamine Dehydrogenase from Nocardioides simplex.
Maiko Tsutsumi, Nobutaka Fujieda, Seiya Tsujimura, Osamu Shirai and Kenji Kano*
Biosci. Biotech. Biochem., 72(3), 786-796 (2008).
2007
- (8) Model Studies of 6,7-Indolequinone Cofactors of Quinohemoprotein Amine Dehydrogenases.
Murakami, Y., Yoshimoto, Nobutaka Fujieda, Kei Ohkubo, Kenji Kano, Shunichi Fukuzumi and Shinobu Itoh*
J. Org. Chem., 72(9), 3369-3380 (2007).
2005
- (7) Production of Completely Flavinylated Histamine Dehydrogenase, Unique Covalently Bound Flavin and Iron-Sulfur Cluster Containing Enzyme, of Nocardioides simplex in Escherichia coli and Its Properties.
Nobutaka Fujieda, Noriaki Tsuse, Astuko Satoh, Tokuji Ikeda, and Kenji Kano*
Biosci. Biotech. Biochem., 69(12), 2459-2462 (2005). - (6) Mediated Spectroelectrochemical Titration of Proteins for Redox Potential Measurements by a Separator-less One-compartment Bulk Electrolysis Method.
Seiya Tsujimura, Atsushi Kuriyama, Nobutaka Fujieda, Kenji Kano, and Tokuji Ikeda*
Anal. Biochem., 337 (2), 325-331 (2005).
2004
- (5) 6-S-Cysteinyl Flavin Mononucleotide-containing Histamine Dehydrogenase from Nocardioides simplex: Molecular Cloning, Sequencing, Over-Expression and Characterization of Redox Centers of Enzyme.
Nobutaka Fujieda, Astuko Satoh, Noriaki Tsuse, Kenji Kano, and Tokuji Ikeda*
Biochemistry, 43 (33), 10800-10808 (2004). - (4) Separator-less One-compartment Bulk Electrolysis with a Small Auxiliary Electrode and Its Application to Spectroelectrochemistry.
Atsushi Kuriyama, Moriaki Arasaki, Nobutaka Fujieda, Seiya Tsujimura, Kenji Kano, and Tokuji Ikeda*
Electrochemistry, 72 (7), 484-486 (2004). - (3) DsbB Elicits a Red-shift of Bound Ubiquinone during the Catalysis of DsbA Oxidation.
Kenji Inaba, Yoh-hei Takahashi, Nobutaka Fujieda, Kenji Kano, Hideto Miyoshi, and Koreaki Ito*
J. Biol. Chem., 279 (8), 6761-6768 (2004).
2003
- (2) Redox Properties of Quinohemoprotein Amine Dehydrogenase from Paracoccus denitrificans.
Nobutaka Fujieda, Megumi Mori, Kenji Kano, and Tokuji Ikeda*
Biochim. Biophys. Acta, 1647 (1/2), 289-296 (2003).
2002
- (1) Spectroelectrochemical Evaluation of Redox Potentials of Cysteine Tryptophylquinone and Two Hemes c in Quinohemoprotein Amine Dehydrogenase from Paracoccus denitrificans.
Nobutaka Fujieda, Megumi Mori, Kenji Kano, and Tokuji Ikeda*
Biochemistry, 41 (46), 13736-13743 (2002).