発表論文
2024
K. Machida, K, Igarashi, H, Kawachi, M, Okamoto, S. Yonezawa, Y. Morishige, M. Azuma, A. Nishiyama
Continuous Sonocrystallization Process for Controlling the Polymorphs and Particle Size of Perampanel
Org. Process Res. Dev., in press (2024)
D. Saito, S. Nerome, M. Tachiwana, Y. Ojima, M. Azuma
Yeast cell wall-derived proteins: identification and characterization as food emulsifiers
Food Hydrocolloids(大学が推奨するTop5雑誌、IF=11.0), 160:110746 (2024)
T. Gamo, Y. Ojima, S. Matsubara, Y. Fukumoto, M. Azuma
Nitrogen conversion performance of a polypropylene carrier designed to promote biofilm formation through foaming
Environmental Technology & Innovation(大学が推奨するTop5雑誌、IF=6.7), 36: 103747 (2024)
Y. Ojima, K. Toda, T. Sawabe, Y. Kumazoe, Y.O. Tahara, M. Miyata, M. Azuma
Budding and explosive membrane vesicle production by hypervesiculating Escherichia coli strain ΔrodZ
Frontiers in Microbiology(IF=5.2), 15:1400434 (2024)
T. Sawabe, Y. Ojima, M. Nakagawa, T. Sawada, Y.O. Tahara, M. Miyata, M. Azuma
Construction and characterization of a hypervesiculation strain of Escherichia coli Nissle 1917
PLOS ONE, 19(4):e0301613 (2024)
S. Matsuura, K. Igarashi, M. Azuma, H. Ooshima
The Solid-Phase Transition of Carbapenem CS-023 Polymorphs and the Change in Helicity Observed in the Transition.
Crystals, 14(1): 71 (2024)
2023
東 雅之、尾島 由紘
代謝改変した大腸菌を触媒とした微生物燃料電池の検討
触媒, 65(5), 276-281 (2023)
S. Matsuura, K. Igarashi, M. Azuma, H. Ooshima
The Identification and Characterization of a New Carbapenem CS-023 Solvate Polymorph Achieved by the Appropriate Crystal Washing and Drying.
J. Chem. Eng.Jpn., 56(1): 2215255 (2023)
Y. Ojima, S. Matano, M. Azuma
Characterization of self-aggregation in Bacillus lichneniformis strain RK14.
Ann. Microbiol., 73:18 (2023)
S. Nerome, M. Tsudzuki, M. Nizuka, M. Takata, Y. Ojima, M. Azuma
Identification of emulsification proteins released from the cells by inhibiting the synthesis of GPI-anchor or β-1,3-glucan in Candida albicans.
J. Microbiol. Methods., 209:106728 (2023)
Y. Ojima, K. Naoi, R. Akiyoshi, M. Azuma
Quantitative analysis of phosphate accumulation in PHO regulatory system-mutant strains of Saccharomyces cerevisiae.
Arch. Microbiol., 205(4):138 (2023)
M. Kihara, Y. Ojima, M. Azuma
Adsorption of rare earth ions from synthetic seawater and hot spring water using phosphorylated yeast.
Environ. Technol. Innov.(IF=7.45), 30:103093 (2023） 科学新聞に掲載(2023/3/31)
2022
東 雅之、尾島 由紘
パン酵母細胞壁に含まれる糖タンパク質の乳化作用
月刊ファインケミカル，51(10), 48-54 (2022)
Y. Ojima, N. Yokota, T. Tanibata, S. Nerome, M. Azuma
Concentrative nucleoside transporter, CNT, results in selective toxicity of toyocamycin against Candida albicans.
Microbiol. Spectr.(IF=7.171), 10(4): e01138 (2022）
尾島 由紘
微生物細胞を鋳型にした触媒合成
生物工学会誌，100(6), 317 (2022)
2021
尾島 由紘，東 雅之
大腸菌の外膜小胞高生産株の作製とタンパク質分泌生産等への利用
酵素工学ニュース，86, 32-35 (2021)
S. Nerome, N. Yokota, Y. Ojima, M. Azuma
Evaluating β-1,3-glucan synthesis inhibition using emulsion formation as an indicator.
J. Microbiol. Methods, 190:106327（2021）
Y. Sumida, M. Yamasaki, Y. Nishiya, S. Kumagai, T. Yamada, M. Azuma
Protein Engineering of D-Succinylase from Cupriavidus sp. for D-Amino Acid Synthesis and the Structural Implications.
Adv. Synth. Catal. (IF=5.837), 363, 1-10 (2021)
S. Matsuura, K. Igarashi, M. Azuma, H. Ooshima
Polymorphic Crystallization Design to Prevent the Degradation of the β-Lactam Structure of a Carbapenem.
Crystals, 11, 931 (2021)
Y. Ojima#, T. Sawabe#, M. Nakagawa, Y.O. Tahara, M. Miyata, and M. Azuma(#筆頭著者)
Aberrant membrane structures in hypervesiculating Escherichia coli strain ΔmlaEΔnlpI visualized by electron microscopy.
Frontiers in Microbiology (IF=5.6), 12:706525 (2021)
尾島 由紘、 東 雅之
外膜小胞に着目した大腸菌のタンパク質分泌生産の試み
化学工業, 72(5), 319-324 (2021)
Y. Ojima, H. Honma, M. Otsuka, S. Matano, M. Azuma,
Enhanced floc formation by degP-deficient Escherichia coli cells in the presence of glycerol.
J. Biosci. Bioeng., 131(1), 33-38 (2021)
M. Onishi, M. Ueda, D. Saito, M. Takata, Y. Ojima, M. Azuma,
Identification of yeast-derived emulsification proteins through analyses of proteins distributed into the emulsified phase.
Food Hydrocoll.(IF=7.053), 112,106321 (2021)
2020
東 雅之、尾島 由紘
パン酵母由来の乳化能を有する糖タンパク質の解析
科学と工業, 94(12), 362-369 (2020)
Y. Ojima#, M. Kihara#, M. Yoshida, K. Igarashi, T. Yoshida, M. Azuma(#筆頭著者)
Mineralization induced by phosphorylated dry baker’s yeast.
PLOS ONE, 15(9),e0239774 (2020)
S. Nerome, M. Onishi, D. Saito, A. Mizobuchi, T. Ando, Y. Daira, A. Matsumoto, Y. Ojima, M. Azuma
Cell surface changes that advance the application of using yeast as a food emulsifier.
Food Chem., 315, 126264(6 pages) (2020)
Y. Ojima, T. Sawabe, K. Konami, M. Azuma
Construction of hypervesiculation Escherichia coli strains and application for secretory protein production.
Biotechnol. Bioeng., 117(3), 701-709 (2020)
Y. Ojima#, T. Kawaguchi#, S. Fukui, R. Kikuchi, K. Terao, D. Koma, T. Ohmoto, M. Azuma(#筆頭著者)
Promoted performance of microbial fuel cells using Escherichia coli cells with multiple-knockout of central metabolism genes.
Bioproc. Biosyst. Eng., 43, 323-332 (2020) Best Paper Award 2020を受賞
2019
尾島由紘
大腸菌の外膜小胞に起因する自発的な凝集形成と菌体分離への利用
化学工学会バイオ部会Newsletter, 49, 3-7 (2019)
Y. Ojima, J. Kobayashi, T. Doi, M. Azuma,
Knockout of pgdS and ggt gene changes poly-γ-glutamic acid production in Bacillus licheniformis RK14-46.
J. Biotechnol., 304, 57-62 (2019)
M. Kishida, K. Igarashi, M. Azuma, H. Ooshima,
Simultaneous Control of Crystal Habit and Particle Size of Ecabet Sodium Hydrate with Rapid Cooling Crystallization and Temperature Cycling.
J. Chem. Eng. Jpn., 52(5), 455-464 (2019)
Y. Ojima#, S. Kosako#, M. Kihara, N. Miyoshi, K. Igarashi, M. Azuma(#筆頭著者)
Recovering metals from aqueous solutions by biosorption onto phosphorylated dry baker’s yeast,
Sci. Rep., 9:225 (2019)
2018
Y. Ojima, M. Azuma, M. Taya,
Inducing flocculation of non-floc-forming Escherichia coli cells (Review)
World J. Microbiol. Biotechnol. 34:185 (2018)
M. Kishida, K. Igarashi, M. Azuma, H. Ooshima
Pharmaceutical Microcrystal Formation by Supersaturation Control with an Electrolyte.
J. Chem. Eng. Jpn., 51(7), 1-6 (2018)
Y. Ojima, S. Nunogami, M. Azuma, M. Taya,
Displaying a recombinant protein on flocs self-produced by Escherichia coli through fused expression with elongation factor Ts.
Enzyme Microb. Technol., 108, 21-25 (2018)
R.W. Nurhayati, Y. Ojima, T. Dohda, M. Kino-oka,
Large-scale culture of a megakaryocytic progenitor cell line with a single-use bioreactor system.
Biotechnol. Prog., 34(2), 362-369 (2018)
T. Liu, H. Nobeshima, Y. Ojima, M. Azuma,
A New Method to Purify Poly-γ-glutamic Acid Using Gemini Quaternary Ammonium Salts and Characterization of its Ionic Complex.
J. Chem. Eng. Jpn., 51(5),431-437 (2018) Editor'a choice賞を受賞
F.M. Kashiwagi, Y. Ojima, M. Taya,
Metabolic Engineering of Escherichia coli KO11 with NADH regeneration system for enhancing ethanol production.
J. Chem. Eng. Jpn., 51(3), 264-268 (2018)
Y. Sumida, S. Iwai, Y. Nishiya, S. Kumagai, T. Yamada, M. Azuma,
Characterization of D-succinylase from Cupriavidus sp. P4-10-C and its application in D-amino acid synthesis.
J. Biosci. Bioeng., 125(3),282-286 (2018)
K. Igarashi, M. Aoki, Y. Masuda, M. Azuma, H. Ooshima
Behavior of t-butoxycarbonyl-L-asparagine (Boc-Asn) during the initial stage of crystallization.
J. Chem. Eng. Jpn., 51(1)111-115 (2018)
Y. Ojima, K. Yamaguchi, M. Taya
Quantitative evaluation of recombinant protein packaged into outer membrane vesicles of Escherichia coli cells.
Biotech. Prog., 34(1), 51-57 (2018)
2017
H. Aiba, Y. Nishiya, Y. Ojima, M. Azuma
Over-expression, characterization and modification of highly active alkaline phosphatase from a Shewanella genus bacterium.
Biosci. Biotechnol. Biochem., 81(10), 1994–2001 (2017)
T. Liu, K. Yamashita, Y. Fukumoto, T. Tachibana, M. Azuma
Flocculation of real sewage sludge using polyglutamic acid produced by Bacillus sp. isolated from soil.
J. Chem. Eng. Jpn., 50(3), 201-206 (2017)
Y. Liu, Y. Ojima, M. Horie, E. Nagamori, H. Fujita
Design and fabrication of devices for investigating cell-sheet stretch.
BioChip J.,11(3), 173–179 (2017)
Y. Ojima, T. Mohanadas, K. Kitamura, S. Nunogami, R. Yajima, M. Taya
Deletion of degQ gene enhances outer membrane vesicle production of Shewanella oneidensis cells.
Arch. Microbiol., 199, 415-423 (2017)
2016
Y. Sumida, S. Iwai, Y. Nishiya, S. Kumagai, T. Yamada, M. Azuma
Identification and characterization of D-succinylase, and a proposed enzymatic method for D-amino acid synthesis.
Adv. Synth. Catal., 358(13), 2041-2046 (2016)
Y. Ojima, S. Nunogami, M. Taya
Antibiofilm effect of warfarin on the biofilm formation of Escherichia coli promoted by antimicrobial treatment.
J. Glob. Antimicrob. Resist., 7, 102-105 (2016)
Y. Ojima, S. Takeda, M. Taya
Floc formation of ethanol producing Escherichia coli KO11 cells and its application to repeated batch operation.
J. Chem. Eng. Jpn., 49(8), 793-798 (2016)