研究業績

研究業績

英文

  • Chan MP, Takenaka N, Abe Y, Satoh T.
    Insulin-stimulated translocation of the fatty acid transporter CD36 to the plasma membrane is mediated by the small GTPase Rac1 in adipocytes.
    Cell Signal 117, 111102 (2024)
  • Chan MP, Takenaka N, Satoh T.
    Impaired insulin signaling mediated by the small GTPase Rac1 in skeletal muscle of the leptin-deficient obese mouse.
    Int J Mol Sci 24 (14), 11531 (2023)
  • Hasegawa K, Takenaka N, Yamamoto M, Sakoda Y, Aiba A, Satoh T.
    Regulation of de novo lipid synthesis by the small GTPase Rac1 in the adipogenic differentiation of progenitor cells from mouse white adipose tissue.
    Int J Mol Sci 24 (05), 4608 (2023)
  • Hasegawa K, Takenaka N, Tanida K, Chan MP, Sakata M, Aiba A, Satoh T.
    Atrophy of white adipose tissue accompanied with decreased insulin-stimulated glucose uptake in mice lacking the small GTPase Rac1 specifically in adipocytes.
    Int J Mol Sci 22 (19), 10753 (2021)
  • Takenaka N, Nakao M, Hasegawa K, Chan MP, Satoh T.
    The guanine nucleotide exchange factor FLJ00068 activates Rac1 in adipocyte insulin signaling.
    FEBS Lett 594 (24), 4370-4380 (2020)
  • Satoh T.
    Diverse physiological functions and regulatory mechanisms for signal-transducing small GTPases.
    Int J Mol Sci 21 (19), 7291 (2020)
  • Satoh TTakenaka N.
    A critical role for the small GTPase Rac1 in insulin signaling that regulates glucose uptake in skeletal muscle.
    Res Chem Intermediat 45 (11), 5389-5397 (2019)
  • Takenaka N, Nakao M, Matsui S, Satoh T.
    A crucial role for the small GTPase Rac1 downstream of the protein kinase Akt2 in insulin signaling that regulates glucose uptake in mouse adipocytes.
    Int J Mol Sci 20, 5443 (2019)
  • Takenaka N, Araki N, Satoh T.
    Involvement of the protein kinase Akt2 in insulin-stimulated Rac1 activation leading to glucose uptake in mouse skeletal muscle.
    PLOS ONE 14 (2), e0212219 (2019)
  • Takenaka NSatoh T.
    ACK1.
    “Encyclopedia of Signaling Molecules (2nd Edition)” (Sangdun Choi, ed; Springer) (Print ISBN: 978-3-319-67198-7, Online ISBN: 978-3-319-67199-4) pp. 102-108 (2017)
  • Takenaka N, Nihata Y, Ueda S, Satoh T.
    In situ detection of the activation of Rac1 and RalA small GTPases in mouse adipocytes by immunofluorescent microscopy following in vivo and ex vivo insulin stimulation.
    Cell Signal 39, 108-117 (2017)
    PMID: 28821441
  • Takenaka N, Nihata Y, Satoh T.
    Rac1 activation caused by membrane translocation of a guanine nucleotide exchange factor in Akt2-mediated insulin signaling in mouse skeletal muscle.
    PLOS ONE 11 (5), e0155292 (2016)
    PMID: 27163697
  • Takenaka N, Sumi Y, Matsuda K, Fujita J, Hosooka T, Noguchi T, Aiba A, Satoh T.
    Role for RalA downstream of Rac1 in skeletal muscle insulin signalling.
    Biochem J 469 (3), 445-454 (2015)
    PMID: 26205497
  • Takenaka N, Nihata Y, Satoh T.
    Immunofluorescent detection of the activation of the small GTPase Rac1 in mouse skeletal muscle fibers.
    Anal Biochem 476, 5-7 (2015)
    PMID: 25277816
  • Satoh T.
    Molecular mechanisms for the regulation of insulin-stimulated glucose uptake by small guanosine triphosphatases in skeletal muscle and adipocytes.
    Int J Mol Sci 15 (10), 18677-18692 (2014)
    PMID: 25325535
  • Nagano T, Edamatsu H, Kobayashi K, Takenaka N, Yamamoto M, Sasaki N, Nishimura Y, Kataoka T.
    Phospholipase Cε, an Effector of Ras and Rap Small GTPases, Is Required for Airway Inflammatory Response in a Mouse Model of Bronchial Asthma.
    PLOS ONE 9 (9), e108373 (2014)
    PMID: 25269075
  • Takenaka N, Yasuda N, Nihata Y, Hosooka T, Noguchi T, Aiba A, Satoh T.
    Role of the guanine nucleotide exchange factor in Akt2-mediated plasma membrane translocation of GLUT4 in insulin-stimulated skeletal muscle.
    Cell Signal 26 (11), 2460-2469 (2014)
    PMID: 25025572
  • Satoh T.
    Rho GTPases in insulin-stimulated glucose uptake.
    Small GTPases 5, e28102 (2014)
    PMID: 24613967
  • Takenaka N, Izawa R, Wu J, Kitagawa K, Nihata Y, Hosooka T, Noguchi T, Ogawa W, Aiba A, Satoh T.
    A critical role of the small GTPase Rac1 in Akt2-mediated GLUT4 translocation in mouse skeletal muscle.
    FEBS J 281 (5), 1493-1504 (2014)
    PMID: 24438685
  • Haredy AM, Takenaka N, Yamada H, Sakoda Y, Okamatsu M, Yamamoto N, Omasa T, Ohtake H, Mori Y, Kida H, Yamanishi K, Okamoto S.
    An MDCK cell culture-derived formalin-inactivated influenza virus whole-virion vaccine from an influenza virus library confers cross-protective immunity by intranasal administration in mice.
    Clin Vaccine Immunol 20 (7), 998-1007 (2013)
    PMID: 23637045
  • Satoh T.
    The Ras superfamily of small GTP-binding proteins in glucose transporter type 4-mediated glucose uptake signaling in insulin-responsive tissues.
    “Glucose Uptake: Regulation, Signaling Pathways and Health Implications” (Carter C. Johnson and Davis B. Williams, ed; Nova Science Publishers, Hauppauge, NY, USA) (ISBN: 978-1-62618-670-5) Chapter 9 (pp. 235-252) (2013)
    (https://www.novapublishers.com/catalog/product_info.php?products_id=43763)
  • Nozaki S, Takeda T, Kitaura T, Takenaka N, Kataoka T, Satoh T.
    Akt2 regulates Rac1 activity in the insulin-dependent signaling pathway leading to GLUT4 translocation to the plasma membrane in skeletal muscle cells.
    Cell Signal 25 (6), 1361-1371 (2013)
    PMID: 23499910
  • Asahara S, Shibutani Y, Teruyama K, Inoue HY, Kawada Y, Etoh H, Matsuda T, Kimura-Koyanagi M, Hashimoto N, Sakahara M, Fujimoto W, Takahashi H, Ueda S, Hosooka T, Satoh T, Inoue H, Matsumoto M, Aiba A, Kasuga M, Kido Y.
    Ras-related C3 botulinum toxin substrate 1 (RAC1) regulates glucose-stimulated insulin secretion via modulation of F-actin.
    Diabetologia 56 (5), 1088-1097 (2013)
    PMID: 23412604
  • Ibi D, Nagai T, Nakajima A, Mizoguchi H, Kawase T, Tsuboi D, Kano SI, Sato Y, Hayakawa M, Lange UC, Adams DJ, Surani MA, Satoh T, Sawa A, Kaibuchi K, Nabeshima T, Yamada K.
    Astroglial IFITM3 mediates neuronal impairments following neonatal immune challenge in mice.
    Glia 61 (5), 679-693 (2013)
    PMID: 23382131
  • Satoh T.
    ACK1.
    “Encyclopedia of Signaling Molecules” (Sangdun Choi, ed; Springer) (ISBN: 978-1-4419-0460-7) pp. 28-33 (2012)
  • Yamada H, Moriishi E, Haredy AM, Takenaka N, Mori Y, Yamanishi K, Okamoto S.
    Influenza virus neuraminidase contributes to the dextran sulfate-dependent suppressive replication of some influenza A virus strains.
    Antiviral Res 96 (3), 344-352 (2012)
    PMID: 23022352
  • Tanimoto T, Haredy AM, Takenaka N, Tamura S, Okuno Y, Mori Y, Yamanishi K, Okamoto S.
    Comparison of the cross-reactive anti-influenza neutralizing activity of polymeric and monomeric IgA monoclonal antibodies.
    Viral Immunol 25 (5), 433-439 (2012)
    PMID: 22985289
  • Nozaki S, Ueda S, Takenaka N, Kataoka T, Satoh T.
    Role of RalA downstream of Rac1 in insulin-dependent glucose uptake in muscle cells.
    Cell Signal 24 (11), 2111-2117 (2012)
    PMID: 22820503
  • Oyaizu H, Tang H, Ota M, Takenaka N, Ozono K, Yamanishi K, Mori Y.
    Complementation of the function of glycoprotein H of human herpesvirus 6 variant A by glycoprotein H of variant B in the virus life cycle.
    J Virol 86 (16), 8492-8498 (2012)
    PMID: 22647694
  • Okamoto S, Matsuoka S, Takenaka N, Haredy AM, Tanimoto T, Gomi Y, Ishikawa T, Akagi T, Akashi M, Okuno Y, Mori Y, Yamanishi K.
    Intranasal immunization with a formalin-inactivated human influenza A virus whole-virion vaccine alone and intranasal immunization with a split-virion vaccine with mucosal adjuvants show similar levels of cross-protection.
    Clin Vaccine Immunol 19 (7), 979-990 (2012)
    PMID: 22552600
  • Edamatsu H,Takenaka N, Hu L, Kataoka T.
    Phospholipase Cε as a potential molecular target for anti-inflammatory therapy and cancer prevention. Inflammation and regeneration.
    Inflamm Regen 31 (4), 370-374 (2011)
  • Bilasy SE, Satoh T, Terashima T, Kataoka T.
    RA-GEF-1 (Rapgef2) is essential for proper development of the midline commissures.
    Neurosci Res 71 (3), 200-209 (2011)
    PMID: 21864586
  • Oka M, Edamatsu H, Kunisada M, Hu L, Takenaka N, Sakaguchi M, Kataoka T, Nishigori C.
    Phospholipase Cɛ has a crucial role in ultraviolet B-induced neutrophil-associated skin inflammation by regulating the expression of CXCL1/KC.
    Lab Invest 91 (5), 711-718 (2011)
    PMID: 21321537
  • Takenaka N, Edamatsu H, Suzuki N, Saito H, Inoue Y, Oka M, Hu L, Kataoka T.
    Overexpression of phospholipase Cε in keratinocytes upregulates cytokine expression and causes dermatitis with acanthosis and T-cell infiltration.
    Eur J Immunol 41 (1), 202-213 (2011)
    PMID: 21182091
  • Oka M, Edamatsu H, Kunisada M, Hu L, Takenaka N, Dien S, Sakaguchi M, Kitazawa R, Norose K, Kataoka T, Nishigori C.
    Enhancement of ultraviolet B-induced skin tumor development in phospholipase Cε-knockout mice is associated with decreased cell death.
    Carcinogenesis 31 (10), 1897-1902 (2010)
    PMID: 20688835
  • Ueda S, Kitazawa S, Ishida K, Nishikawa Y, Matsui M, Matsumoto H, Aoki T, Nozaki S, Takeda T, Tamori Y, Aiba A, Kahn CR, Kataoka T, Satoh T.
    Crucial role of the small GTPase Rac1 in insulin-stimulated translocation of glucose transporter 4 to the mouse skeletal muscle sarcolemma.
    FASEB J 24 (7), 2254-2261 (2010)
    PMID: 20203090
  • Hu L, Edamatsu H, Takenaka N, Ikuta S, Kataoka T.
    Crucial role of phospholipase Cε in induction of local skin inflammatory reactions in the elicitation stage of allergic contact hypersensitivity.
    J Immunol 184 (2), 993-1002 (2010)
    PMID: 20007527
  • Ono R, Kumagai H, Nakajima H, Hishiya A, Taki T, Horikawa K, Takatsu K, Satoh T, Hayashi Y, Kitamura T, Nosaka T.
    Mixed-lineage-leukemia (MLL) fusion protein collaborates with Ras to induce acute leukemia through aberrant Hox expression and Raf activation.
    Leukemia 23 (12), 2197-2209 (2009)
    PMID: 19710696
  • Kanemura H, Satoh T, Bilasy SE, Ueda S, Hirashima M, Kataoka T.
    Impaired vascular development in the yolk sac and allantois in mice lacking RA-GEF-1.
    Biochem Biophys Res Commun 387 (4), 754-759 (2009)
    PMID: 19635461
  • Aoki T, Ueda S, Kataoka T, Satoh T.
    Regulation of mitotic spindle formation by the RhoA guanine nucleotide exchange factor ARHGEF10.
    BMC Cell Biol 10, 56 (2009)
    PMID: 19635168
  • Bilasy SE, Satoh T, Ueda S, Wei P, Kanemura H, Aiba A, Terashima T, Kataoka T.
    Dorsal telencephalon-specific RA-GEF-1 knockout mice develop heterotopic cortical mass and commissural fiber defect.
    Eur J Neurosci 29 (10), 1994-2008 (2009)
    PMID: 19453629
  • Ueda S, Kataoka T, Satoh T.
    Activation of the small GTPase Rac1 by a specific guanine-nucleotide-exchange factor suffices to induce glucose uptake into skeletal-muscle cells.
    Biol Cell 100 (11), 645-657 (2008)
    PMID: 18482007
  • Satoh T.
    The signaling network of Ras family and Rho family GTP-binding proteins in mammalian cells.
    “Cellular Signaling and Apoptosis Research” (Alex R. Demasi, ed; Nova Science Publishers, Hauppauge, NY, USA) (ISBN: 978-1-60021-565-0) Chapter 8 (pp. 221-246) (2007)
  • Shibasaki T, Takahashi H, Miki T, Sunaga Y, Matsumura K, Yamanaka M, Zhang C, Tamamoto A, Satoh T, Miyazaki J, Seino S.
    Essential role of Epac2/Rap1 signaling in regulation of insulin granule dynamics by cAMP.
    Proc Natl Acad Sci USA 104 (49), 19333-19338 (2007)
    PMID: 18040047
  • Wei P, Satoh T, Edamatsu H, Aiba A, Setsu T, Terashima T, Kitazawa S, Nakao K, Yoshikawa Y, Tamada M, Kataoka T.
    Defective vascular morphogenesis and mid-gestation embryonic death in mice lacking RA-GEF-1.
    Biochem Biophys Res Commun 363 (1), 106-112 (2007)
    PMID: 17826737
  • Yoshikawa Y, Satoh T, Tamura T, Wei P, Bilasy SE, Edamatsu H, Aiba A, Katagiri K, Kinashi T, Nakao K, Kataoka T.
    The M-Ras-RA-GEF-2-Rap1 pathway mediates tumor necrosis factor-α dependent regulation of integrin activation in splenocytes.
    Mol Biol Cell 18 (8), 2949-2959 (2007)
    PMID: 17538012
  • Ieguchi K, Ueda S, Kataoka T, Satoh T.
    Role of the guanine nucleotide exchange factor Ost in negative regulation of receptor endocytosis by the small GTPase Rac1.
    J Biol Chem 282 (32), 23296-23305 (2007)
    PMID: 17562712
  • Satoh T, Edamatsu H, Kataoka T.
    Phospholipase Cε guanine nucleotide exchange factor activity and activation of Rap1.
    Methods Enzymol 407, 281-290 (2006)
    PMID:16757332
  • Edamatsu H, Satoh T, Kataoka T.
    Ras and Rap1 activation of PLCε lipase activity.
    Methods Enzymol 407, 99-107 (2006)
    PMID:16757317
  • Satoh T.
    ACK1.
    “UCSD-Nature The Signaling Gateway Molecule Pages” A000186 (doi: 10.1038/mp.a000186.01) (2005)
  • Nur-E-Kamal A, Zhang A, Keenan SM, Wang XI, Seraj J, Satoh T, Meiners S, Welsh WJ.
    Requirement of activated Cdc42-associated kinase for survival of v-Ras-transformed mammalian cells.
    Mol Cancer Res 3 (5), 297-305 (2005)
    PMID: 15886301
  • Tadano M, Edamatsu H, Minamisawa S, Yokoyama U, Ishikawa Y, Suzuki N, Saito H, Wu D, Masago-Toda M, Yamawaki-Kataoka Y, Setsu T, Terashima T, Maeda S, Satoh T, Kataoka T.
    Congenital semilunar valvulogenesis defect in mice deficient in phospholipase Cε.
    Mol Cell Biol 25 (6), 2191-2199 (2005)
    PMID: 15743817
  • Bai Y, Edamatsu H, Maeda S, Saito H, Suzuki N, Satoh T, Kataoka T.
    Crucial role of phospholipase Cε in chemical carcinogen-induced skin tumor development.
    Cancer Res 64 (24), 8808-8810 (2004)
    PMID: 15604236
  • Ueda S, Kataoka T, Satoh T.
    Role of the Sec14-like domain of Dbl family exchange factors in the regulation of Rho family GTPases in different subcellular sites.
    Cell Signal 16 (8), 899-906 (2004)
    PMID: 15157669
  • Nomura K, Kanemura H, Satoh T, Kataoka T.
    Identification of a novel domain of Ras and Rap1 that directs their differential subcellular localizations.
    J Biol Chem 279 (21), 22664-22673 (2004)
    PMID: 15031297
  • Honma N, Asada A, Takeshita S, Enomoto M, Yamakawa E, Tsutsumi K, Saito T, Satoh T, Itoh H, Kaziro Y, Kishimoto T, Hisanaga S.
    Apoptosis-associated tyrosine kinase is a Cdk5 activator p35 binding protein.
    Biochem Biophys Res Commun 310 (2), 398-404 (2003)
    PMID: 14521924
  • Wu D, Tadano M, Edamatsu H, Masago-Toda M, Yamawaki-Kataoka Y, Terashima T, Mizoguchi A, Minami Y, Satoh T, Kataoka T.
    Neuronal lineage-specific induction of phospholipase Cε expression in the developing mouse brain.
    Eur J Neurosci 17 (8), 1571-1580 (2003)
    PMID: 12752375
  • Minoshima Y, Kawashima T, Hirose K, Tonozuka Y, Kawajiri A, Bao YC, Deng X, Tatsuka M, Narumiya S, May WS Jr, Nosaka T, Semba K, Inoue T, Satoh T, Inagaki M, Kitamura T.
    Phosphorylation by aurora B converts MgcRacGAP to a RhoGAP during cytokinesis.
    Dev Cell 4 (4), 549-560 (2003)
    PMID: 12689593
  • Song C, Satoh T, Edamatsu H, Wu D, Tadano M, Gao X, Kataoka T.
    Differential roles of Ras and Rap1 in growth factor-dependent activation of phospholipase Cε.
    Oncogene 21 (53), 8105-8113 (2002)
    PMID: 12444546
  • Kido M, Shima F, Satoh T, Asato T, Kariya K, Kataoka T.
    Critical function of the Ras-associating domain as a primary Ras-binding site for regulation of Saccharomyces cerevisiae adenylyl cyclase.
    J Biol Chem 277 (5), 3117-3123 (2002)
    PMID: 11723130
  • Gao X, Satoh T, Liao Y, Song C, Hu CD, Kariya Ki K, Kataoka T.
    Identification and characterization of RA-GEF-2, a Rap guanine nucleotide exchange factor that serves as a downstream target of M-Ras.
    J Biol Chem 276 (45), 42219-42225 (2001)
    PMID: 11524421
  • Jin TG, Satoh T, Liao Y, Song C, Gao X, Kariya K, Hu CD, Kataoka T.
    Role of the CDC25 homology domain of phospholipase Cε in amplification of Rap1-dependent signaling.
    J Biol Chem 276 (32), 30301-30307 (2001)
    PMID: 11395506
  • Liao Y, Satoh T, Gao X, Jin TG, Hu CD, Kataoka T.
    RA-GEF-1, a guanine nucleotide exchange factor for Rap1, is activated by translocation induced by association with Rap1·GTP and enhances Rap1-dependent B-Raf activation.
    J Biol Chem 276 (30), 28478-28483 (2001)
    PMID: 11359771
  • Kato-Stankiewicz J, Ueda S, Kataoka T, Kaziro Y, Satoh T.
    Epidermal growth factor stimulation of the ACK1/Dbl pathway in a Cdc42 and Grb2-dependent manner.
    Biochem Biophys Res Commun 284 (2), 470-477 (2001)
    PMID: 11394904
  • Song C, Hu CD, Masago M, Kariyai K, Yamawaki-Kataoka Y, Shibatohge M, Wu D, Satoh T, Kataoka T.
    Regulation of a novel human phospholipase C, PLCε, through membrane targeting by Ras.
    J Biol Chem 276 (4), 2752-2757 (2001)
    PMID: 11022048
  • Kiyono M, Kato J, Kataoka T, Kaziro Y, Satoh T.
    Stimulation of Ras guanine nucleotide exchange activity of Ras-GRF1/CDC25Mm upon tyrosine phosphorylation by the Cdc42-regulated kinase ACK1.
    J Biol Chem 275 (38), 29788-29793 (2000)
    PMID: 10882715
  • Kawashima T, Hirose K, Satoh T, Kaneko A, Ikeda Y, Kaziro Y, Nosaka T, Kitamura T.
    MgcRacGAP is involved in the control of growth and differentiation of hematopoietic cells.
    Blood 96 (6), 2116-2124 (2000)
    PMID: 10979956
  • Kiyono M, Kaziro Y, Satoh T.
    Induction of rac-guanine nucleotide exchange activity of Ras-GRF1/CDC25Mm following phosphorylation by the nonreceptor tyrosine kinase Src.
    J Biol Chem 275 (8), 5441-5446 (2000)
    PMID: 10681520
  • Kato J, Kaziro Y, Satoh T.
    Activation of the guanine nucleotide exchange factor Dbl following ACK1-dependent tyrosine phosphorylation.
    Biochem Biophys Res Commun 268 (1), 141-147 (2000)
    PMID: 10652228
  • Terada K, Kaziro Y, Satoh T.
    Analysis of Ras-dependent signals that prevent caspase-3 activation and apoptosis induced by cytokine deprivation in hematopoietic cells.
    Biochem Biophys Res Commun 267 (1), 449-455 (2000)
    PMID: 10623640
  • Nishida K, Kaziro Y, Satoh T.
    Association of the proto-oncogene product dbl with G protein βγ subunits.
    FEBS Lett 459 (2), 186-190 (1999)
    PMID: 10518015
  • Kiyono M, Satoh T, Kaziro Y.
    G protein βγ subunit-dependent Rac-guanine nucleotide exchange activity of Ras-GRF1/CDC25Mm.
    Proc Natl Acad Sci USA 96 (9), 4826-4831 (1999)
    PMID: 10220378
  • Nishida K, Kaziro Y, Satoh T.
    Anti-apoptotic function of Rac in hematopoietic cells.
    Oncogene 18 (2), 407-415 (1999)
    PMID: 9927197
  • Deng J, Kawakami Y, Hartman SE, Satoh T, Kawakami T.
    Involvement of Ras in Bruton’s tyrosine kinase-mediated JNK activation.
    J Biol Chem 273 (27), 16787-16791 (1998)
    PMID: 9642236
  • Tago K, Kaziro Y, Satoh T.
    Functional involvement of mSos in interleukin-3 and thrombin stimulation of the Ras, mitogen-activated protein kinase pathway in BaF3 murine hematopoietic cells.
    J Biochem 123 (4), 659-667 (1998)
    PMID: 9538258
  • Terada K, Kaziro Y, Satoh T.
    Ras-dependent activation of c-Jun N-terminal kinase/stress-activated protein kinase in response to interleukin-3 stimulation in hematopoietic BaF3 cells.
    J Biol Chem 272 (7), 4544-4548 (1997)
    PMID: 9020181
  • Satoh T, Kato J, Nishida K, Kaziro Y.
    Tyrosine phosphorylation of ACK in response to temperature shift-down, hyperosmotic shock, and epidermal growth factor stimulation.
    FEBS Lett 386(2-3), 230-234 (1996)
    PMID: 8647288
  • Ohtsuka T, Kaziro Y, Satoh T.
    Analysis of the T-cell activation signaling pathway mediated by tyrosine kinases, protein kinase C, and Ras protein, which is modulated by intracellular cyclic AMP.
    Biochim Biophys Acta (Mol Cell Res) 1310 (2), 223-232 (1996)
    PMID: 8611637
  • Satoh T, Kaziro Y.
    Measurement of Ras-bound guanine nucleotide in stimulated hematopoietic cells.
    Methods Enzymol 255, 149-155 (1995)
    PMID: 8524098
  • Mori S, Satoh T, Koide H, Nakafuku M, Villafranca E, Kaziro Y.
    Inhibition of Ras/Raf interaction by anti-oncogenic mutants of neurofibromin, the neurofibromatosis type 1 (NF1) gene product, in cell-free systems.
    J Biol Chem 270 (48), 28834-28838 (1995)
    PMID: 7499408
  • Terada K, Kaziro Y, Satoh T.
    Ras is not required for the interleukin 3-induced proliferation of a mouse pro-B cell line, BaF3.
    J Biol Chem 270 (46), 27880-27886 (1995)
    PMID: 7499262
  • Ito A, Satoh T, Kaziro Y, Itoh H.
    G protein βγ subunit activates Ras, Raf, and MAP kinase in HEK 293 cells.
    FEBS Lett 368 (1), 183-187 (1995)
    PMID: 7615078
  • Davis MM, Catino JJ, Satoh T, Kaziro Y, Perkins LM.
    Sequence of the cDNA encoding Ras GTPase-activating protein from rat.
    Gene 134 (2), 305-306 (1993)
    PMID: 8262392
  • Koide H, Satoh T, Nakafuku M, Kaziro Y.
    GTP-dependent association of Raf-1 with Ha-Ras: identification of Raf as a target downstream of Ras in mammalian cells.
    Proc Natl Acad Sci USA 90 (18), 8683-8686 (1993)
    PMID: 8378348
  • Satoh T, Fantl WJ, Escobedo JA, Williams LT, Kaziro Y.
    Platelet-derived growth factor receptor mediates activation of ras through different signaling pathways in different cell types.
    Mol Cell Biol 13 (6), 3706-3713 (1993)
    PMID: 8388543
  • Satoh T, Nakafuku M, Kaziro Y.
    Function of Ras as a molecular switch in signal transduction.
    J Biol Chem 267 (34), 24149-24152 (1992)
    PMID: 1447166
  • Satoh T, Kaziro Y.
    Ras in signal transduction.
    Semin Cancer Biol 3 (4), 169-177 (1992)
    PMID: 1421161
  • Satoh T, Minami Y, Kono T, Yamada K, Kawahara A, Taniguchi T, Kaziro Y.
    Interleukin 2-induced activation of Ras requires two domains of interleukin 2 receptor β subunit, the essential region for growth stimulation and Lck-binding domain.
    J Biol Chem 267 (35), 25423-25427 (1992)
    PMID: 1460037
  • Nakafuku M, Satoh T, Kaziro Y.
    Differentiation factors, including nerve growth factor, fibroblast growth factor, and interleukin-6, induce an accumulation of an active Ras.GTP complex in rat pheochromocytoma PC12 cells.
    J Biol Chem 267 (27), 19448-19454 (1992)
    PMID: 1527065
  • Satoh T, Uehara Y, Kaziro Y.
    Inhibition of interleukin 3 and granulocyte-macrophage colony-stimulating factor stimulated increase of active ras.GTP by herbimycin A, a specific inhibitor of tyrosine kinases.
    J Biol Chem 267 (4), 2537-2541 (1992)
    PMID: 1733950
  • Kaziro Y, Itoh H, Kozasa T, Nakafuku M, Satoh T.
    Structure and function of signal-transducing GTP-binding proteins.
    Annu Rev Biochem 60, 349-400 (1991)
    PMID: 1909108
  • Satoh T, Nakafuku M, Miyajima A, Kaziro Y.
    Involvement of ras p21 protein in signal-transduction pathways from interleukin 2, interleukin 3, and granulocyte/macrophage colony-stimulating factor, but not from interleukin 4.
    Proc Natl Acad Sci USA 88 (8), 3314-3318 (1991)
    PMID: 1826565
  • Nagata K, Satoh T, Itoh H, Kozasa T, Okano Y, Doi T, Kaziro Y, Nozawa Y.
    The ram: a novel low molecular weight GTP-binding protein cDNA from a rat megakaryocyte library.
    FEBS Lett 275 (1-2), 29-32 (1990)
    PMID: 2124544
  • Satoh T, Endo M, Nakafuku M, Akiyama T, Yamamoto T, Kaziro Y.
    Accumulation of p21ras.GTP in response to stimulation with epidermal growth factor and oncogene products with tyrosine kinase activity.
    Proc Natl Acad Sci USA 87 (20), 7926-7929 (1990)
    PMID: 2146678
  • Satoh T, Endo M, Nakafuku M, Nakamura S, Kaziro Y.
    Platelet-derived growth factor stimulates formation of active p21ras.GTP complex in Swiss mouse 3T3 cells.
    Proc Natl Acad Sci USA 87 (15), 5993-5997 (1990)
    PMID: 2198577
  • Tanaka K, Nakafuku M, Satoh T, Marshall MS, Gibbs JB, Matsumoto K, Kaziro Y, Toh-e A.
    S. cerevisiae genes IRA1 and IRA2 encode proteins that may be functionally equivalent to mammalian ras GTPase activating protein.
    Cell 60 (5), 803-807 (1990)
    PMID: 2178777
  • Satoh T, Nakamura S, Taga T, Matsuda T, Hirano T, Kishimoto T, Kaziro Y.
    Induction of neuronal differentiation in PC12 cells by B-cell stimulatory factor 2/interleukin 6.
    Mol Cell Biol 8 (8), 3546-3549 (1988)
    PMID: 3264880
  • Satoh T, Endo M, Nakamura S, Kaziro Y.
    Analysis of guanine nucleotide bound to ras protein in PC12 cells.
    FEBS Lett 236 (1), 185-189 (1988)
    PMID: 3042464
  • Satoh T, Nakamura S, Nakafuku M, Kaziro Y.
    Studies on ras proteins. Catalytic properties of normal and activated ras proteins purified in the absence of protein denaturants.
    Biochim Biophys Acta (Gene Struct Expr) 949 (1), 97-109 (1988)
    PMID: 3275466
  • Satoh T, Nakamura S, Kaziro Y.
    Induction of neurite formation in PC12 cells by microinjection of proto-oncogenic Ha-ras protein preincubated with guanosine-5′-O-(3-thiotriphosphate).
    Mol Cell Biol 7 (12), 4553-4556 (1987)
    PMID: 3325827
  • Hattori S, Clanton DJ, Satoh T, Nakamura S, Kaziro Y, Kawakita M, Shih TY.
    Neutralizing monoclonal antibody against ras oncogene product p21 which impairs guanine nucleotide exchange.
    Mol Cell Biol 7 (5), 1999-2002 (1987)
    PMID: 2439901

和文

  • 佐藤孝哉
    GTP結合タンパク質の研究―上代淑人(1929-2011).
    生体の科学 増大号特集「現代医学・生物学の先駆者たち」(岡本仁,栗原裕基,松田道行,野々村禎昭 編,公益財団法人金原一郎記念医学医療振興財団/医学書院)70 (5), 394-395 (2019)
  • 佐藤孝哉
    「細胞のシグナル伝達−システムとしての共通原理にもとづく理解−」(西田栄介 監訳,メディカル・サイエンス・インターナショナル)(原著:Wendell Lim, Bruce Mayer, Tony Pawson “Cell Signaling: Principles and Mechanisms” Garland Science, Taylor & Francis Group)第3章 / 用語解説(翻訳)(2016)
  • 佐藤孝哉竹中延之
    ウェスタンブロット.
    「バイオサイエンス実験 入門から応用へ」(大阪府立大学生命環境科学域自然科学類生物科学課程 編,大阪公立大学共同出版会)47-53 (2016)
  • 佐藤孝哉
    RASスーパーファミリー.
    岩波生物学辞典(第5版)(巌佐庸,倉谷滋,斎藤成也,塚谷裕一 編,岩波書店)1435 (2013)
  • 佐藤孝哉
    「デブリン生化学 −臨床の理解のために−(原書7版)」(上代淑人,澁谷正史,井原康夫 監訳,丸善出版)(原著:Thomas M. Devlin, ed “Textbook of Biochemistry: With Clinical Correlations, Seventh Edition” John Wiley & Sons, Inc.)第3章(翻訳)(2012)
  • 佐藤孝哉
    低分子量Gタンパク質.
    「イラストで徹底理解するシグナル伝達キーワード事典」(山本雅,仙波憲太郎,山梨祐司 編,羊土社)19-20 (2012)
  • 佐藤孝哉
    「シグナル伝達 −生命システムの情報ネットワーク−(第2版)」(上代淑人,佐藤孝哉 監訳,メディカル・サイエンス・インターナショナル)(原著:Bastien D. Gomperts, Ijsbrand M. Kramer, Peter E. R. Tatham “Signal Transduction Second Edition” Academic Press/Elsevier Inc.)監訳、第1章 / 第2章 / 第3章 / 第4章/ 第19章(翻訳)(2011)
  • 佐藤孝哉
    低分子量GTP結合タンパク質と神経 / 抑制性シナプスにおけるグリシン受容体のクラスタリングを制御するRhoファミリーGTP結合タンパク質 / 軸索ガイダンスを制御するグアニンヌクレオチド交換因子.
    バイオ研究マスターシリーズ 「シグナル伝達集中マスター」(山本雅,仙波憲太郎 編,羊土社)49-57 / 118-119 / 119 (2005)
  • 佐藤孝哉
    「シグナル伝達 −生命システムの情報ネットワーク−」(上代淑人 監訳,メディカル・サイエンス・インターナショナル)(原著:Bastien D. Gomperts, Ijsbrand M. Kramer, Peter E. R. Tatham “Signal Transduction” Academic Press/Elsevier Science (USA))第2章 / 第3章 / 第4章(翻訳) (2004)
  • 佐藤孝哉
    Rasによる発癌の分子機構.
    Biotherapy 17 (6), 515-521 (2003)
  • 佐藤孝哉,片岡徹:
    Rasを介するシグナル伝達と癌.
    Molecular Medicine 39 (11), 1238-1246 (2002)
  • 佐藤孝哉,上代淑人:
    高等動物細胞におけるRasを介するシグナル伝達系の機能.
    シリ−ズ分子生物学 3巻「高等動物の分子生物学」(村松正實 編,朝倉書店)109-121 (1998)
  • 多胡憲治,佐藤孝哉,上代淑人:
    rasファミリー / GAP.
    Bio Science用語ライブラリー 「癌遺伝子・癌抑制遺伝子」(田矢洋一,山本雅 編,羊土社)20-21 / 156-157 (1997)
  • 小出寛,佐藤孝哉,上代淑人:
    Rasをターゲットとしたがん治療.ファルネシル基転移酵素阻害剤を用いた手法.
    細胞工学16 (8), 1158-1165 (1997)
  • 佐藤孝哉,上代淑人:
    Ras,MAPキナーゼとシグナル伝達.
    医学のあゆみ182 (1), 18-22 (1997)
    医学のあゆみ 別冊「シグナル伝達からみた癌の分子機構」(平井久丸 編,医歯薬出版)18-22 (1999)
  • 佐藤孝哉,上代淑人:
    rasがん遺伝子と細胞内シグナル伝達系.
    現代化学 増刊33「がん遺伝子研究の展望II」(野田亮 編,東京化学同人)8-17 (1997)
  • 佐藤孝哉,上代淑人:
    癌と情報伝達系.
    産科と婦人科64 (1), 29-35 (1997)
  • 佐藤孝哉,上代淑人:
    GTP結合蛋白質とMAPキナーゼスーパーファミリー.
    実験医学14 (19), 2629-2635 (1996)
  • 佐藤孝哉,上代淑人:
    Ras活性化の分子機構.
    実験医学 14巻増刊「GTP結合蛋白質」(高井義美,堅田利明,成宮周 編,羊土社)132-136 [14 (2), 244-248] (1996)
  • 佐藤孝哉,上代淑人:
    Rasタンパク質とその調節因子.
    医学のあゆみ171 (5), 327-330 (1994)
  • 佐藤孝哉,上代淑人:
    シグナルトランスダクションにおけるRas蛋白質の機能.
    「分子糖尿病学の進歩 −基礎から臨床まで− 1994」(門脇孝,春日雅人,清野進,渥美義仁 編,金原出版)74-82 (1994)
  • 佐藤孝哉
    NGFのシグナル伝達とRas蛋白質.
    実験医学10 (19), 2469-2473 (1992)
  • 佐藤孝哉,大塚智一,上代淑人:
    Ras蛋白質と血球系細胞のシグナル伝達.
    代謝 29巻増刊号「免疫’92」(岸本忠三,多田富雄 監編,中山書店)107-114 (1992)
  • 佐藤孝哉,上代淑人:
    サイトカインのシグナル伝達系とRasタンパク質.
    血液・腫瘍科24 (5), 390-398 (1992)
  • 佐藤孝哉,中福雅人,上代淑人:
    Rasタンパク質を介するシグナル伝達系と神経系の分化.
    細胞工学11 (5), 330-336 (1992)
  • 中福雅人,佐藤孝哉,上代淑人:
    GTP結合タンパク質による細胞増殖の制御.
    最新医学46 (9), 1884-1892 (1991)
  • 佐藤孝哉,上代淑人:
    シグナルトランスデュ−サ−としてのRas蛋白質の機能.
    実験医学 9巻増刊「癌化と増殖のシグナル伝達」(竹縄忠臣,秋山徹 編,羊土社)96-102 [9 (13), 1586-1592] (1991)
  • 佐藤孝哉
    GAP / p21 / マイクロインジェクション / ras遺伝子.
    生化学辞典(第2版)(大島泰郎,太田隆久,香川靖雄,上代淑人,鈴木紘一,背山洋右,永井克孝,野島庄七 編,東京化学同人)333 / 1066 / 1289 / 1391 (1990)
  • 佐藤孝哉,上代淑人:
    細胞の分化とras p21の活性制御.
    実験医学 8巻増刊「GTP結合蛋白質と情報伝達」(高井義美,堅田利明 編,羊土社)160-164 [8 (14), 1840-1844] (1990)
  • 佐藤孝哉,上代淑人:
    マイクロインジェクション法.
    新生化学実験講座 8巻「細胞内情報と細胞応答」(日本生化学会 編,東京化学同人)231-236 (1990)
  • 佐藤孝哉,上代淑人:
    GTP結合蛋白質と細胞がん化.
    生体の科学41 (1), 21-25 (1990)
  • 佐藤孝哉
    ニューロロイキン / アストロサイトーマ・グリオブラストーマ.
    Medical Immunology 18 (3), 381 (1989)
  • 佐藤孝哉,上代淑人:
    神経細胞の分化とサイトカイン.
    Medical Immunology 18 (3), 256-258 (1989)
  • 佐藤孝哉
    マイクロインジェクション.
    生化学61 (2), 145 (1989)
  • 佐藤孝哉,上代淑人:
    シグナル伝達における癌遺伝子産物の機能.
    シリ−ズ分子生物学の進歩 12巻「細胞癌化の分子機構」(豊島久真男,吉田光昭 編,丸善)93-122 (1989)
  • 佐藤孝哉,上代淑人:
    神経分化とIL-6.
    実験医学7 (1), 44-49 (1989)
  • 佐藤孝哉,上代淑人:
    癌遺伝子 −ras遺伝子の構造と機能−.
    代謝 25巻臨時増刊号「代謝病ハイライト」(岡博,織田敏次,東野一彌,和田博 編,中山書店)463-467 (1988)